Immortalized Cell Lines CIAI

Immortalized liver cell lines

Core personnel maintain an inventory of several transformed liver cell lines.  Cells can be provided as frozen stock or plated in culture.  Please inquire for further details, including pricing. 

NameSpeciesCell typeSourceGenetic mutations
SNU-449HumanHepatocellular carcinomaATCC CRL-2234CDKN2A, CDKN2a, TP53
SNU-475HumanHepatocellular carcinomaATCC CRL-2236TP53
SNU-387HumanHepatocellular carcinomaATCC CRL-2237CDKN2A, CDKN2a, NRAS, TP53
SNU-423HumanHepatocellular carcinomaATCC CRL-2238Not determined
C3A [HepG2/C3A]HumanHepatocellular carcinomaATCC CRL-10741CTNNB1, NRAS
PLC/PRF/5HumanHepatocellular carcinomaATCC CRL-8024CDKN2A, STK11, TP53
HepG2HumanHepatocellular carcinomaATCC HB-8065 
SK-HEP-1HumanMetastatic adenocarcinomaATCC HTB-52BRAF, CDKN2A, CDKN2a
Huh-7HumanHepatocellular carcinomaJCRB0403, Japanese Cancer Research Resources Bank 
LX-2HumanStellate cellEMD Millipore SCC064