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Fostering innovation and collaboration in liver research
About the Liver Center
The UCSF Liver Center is one of 17 Digestive Diseases Research Core Centers (DDRCC) in the United States, whose purpose is to enhance research productivity and collaboration among scientists with similar interests.
Research Themes of the Center
The overall focus of the Center is on integrative biology of the liver. Research in the Center is organized into 3 themes: Liver Injury, Repair & Transplantation​, Hepatic Metabolism & Metabolic Derangements, Liver Cell Biology, Plasticity & Transformation​.
Core Services of the Center
The Liver Center operates four biomedical core facilities to expedite and enhance the research performed by Center members. The Cores are designed to provide liver-specific services that are unavailable elsewhere within or outside UCSF.

​Welcome to the UCSF Liver Center

The Liver Center is a consortium of 60 researchers who share a common interest in liver biology and disease. The goal of the Center is to integrate bench science with clinical investigation, in support of its vision to understand and cure human liver diseases.

The physicians and scientists of the Liver Center are committed to improving understanding of liver biology and alleviating suffering from liver diseases. Read More.

Jacquelyn Maher, MD

Program Director, Liver Center

 


Featured Publications

Roberts DE, Kakar S, Mehta N, Gill RM. A Point-based Histologic Scoring System for Hepatocellular Carcinoma Can Stratify Risk of Posttransplant Tumor Recurrence. Am J Surg Pathol. 2018 Jul;42(7):855-865. doi: 10.1097/PAS.0000000000001053. PubMed

Schaub JR, Huppert KA, Kurial SNT, Hsu BY, Cast AE, Donnelly B, Karns RA, Chen F, Rezvani M, Luu HY, Mattis AN, Rougemont AL, Rosenthal P, Huppert SS, Willenbring H. De novo formation of the biliary system by TGFβ-mediated hepatocyte transdifferentiation. Nature. 2018 May;557(7704):247-251. doi: 10.1038/s41586-018-0075-5. Epub 2018 May 2. PubMed

Perito ER, Roll G, Dodge JL, Rhee S, Roberts JP. Split liver transplantation and pediatric waitlist mortality in the United States: potential for improvement. Transplantation. 2018 Apr 21. doi:  10.1097/TP.0000000000002249. [Epub ahead of print] PubMed

Publicover J, Gaggar A, Jespersen JM, Halac U, Johnson AJ, Goodsell A, Avanesyan L, Nishimura SL, Holdorf M, Mansfield KG, Judge JB, Koshti A, Croft M, Wakil AE, Rosenthal P, Pai E, Cooper SBaron JL. An OX40/OX40L interaction directs successful immunity to hepatitis B virus. Sci Transl Med. 2018 Mar 21;10(433). pii: eaah5766. doi: 10.1126/scitranslmed.aah5766. PubMed


Upcoming National & International Conferences

 


 


Liver Center News

2018 Pilot/Feasibility Grant Awardees

Jennifer Chen, MD
 

Dissecting the role of YAP and TAZ in hepatic stellate activation and liver fibrosis

Caroline Duwaerts, PhD
 

The role of regulated IRE1 dependent decay (RIDD) in endoplasmic reticulum stress-induced liver cell death

 

Aras Mattis, MD, PhD
 

Discovery of novel genes regulating intrahepatic steatosis in mice and humans


 

Suzanne Sharpton, MD
 

An integrated analysis of the human gut metabolome and metagenome in nonalcoholic fatty liver disease