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Fostering innovation and collaboration in liver research
About the Liver Center
The UCSF Liver Center is one of 17 Digestive Diseases Research Core Centers (DDRCC) in the United States, whose purpose is to enhance research productivity and collaboration among scientists with similar interests.
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Research Themes of the Center
The overall focus of the Center is on integrative biology of the liver. Research in the Center is organized into 3 themes: Liver Injury, Repair & Transplantation​, Hepatic Metabolism & Metabolic Derangements, Liver Cell Biology, Plasticity & Transformation​.
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Core Services of the Center
The Liver Center operates four biomedical core facilities to expedite and enhance the research performed by Center members. The Cores are designed to provide liver-specific services that are unavailable elsewhere within or outside UCSF.
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​Welcome to the UCSF Liver Center

The Liver Center is a consortium of 60 researchers who share a common interest in liver biology and disease. The goal of the Center is to integrate bench science with clinical investigation, in support of its vision to understand and cure human liver diseases.

The physicians and scientists of the Liver Center are committed to improving understanding of liver biology and alleviating suffering from liver diseases. Read More.

Jacquelyn Maher, MD

Program Director, Liver Center

Liver Center News

The Liver Meeting is going digital in 2020!

Abstract deadline is July 17. 
Follow this link for instructions on registration and abstract submissions.


Congratulations to the 2020 Pilot/Feasibility Grant Awardees!

James Lee, MD

Overcoming liver metastasis induced systemic immune tolerance and immunotherapy resistance

Peter Turnbaugh, PhD

Systematic discovery of gut microbial strains and metabolites that boost hepatic drug clearance

Feng Chen, PhD

Examining hepatocyte regenerative behavior at single cell resolution

 

Featured Publications

Alkhani A, Levy CS, Tsui M, Rosenberg KA, Polovina K, Mattis AN, Mack M, Van Dyken S, Wang BM, Maher JJ, Nijagal A. Ly6c-Lo non-classical monocytes promote resolution of rhesus rotavirus-mediated perinatal hepatic inflammation. Sci Rep. 2020 Apr 28;10(1):7165. PMID:32346042; PMCID:PMC7188847.

Sarkar M, Grab J, Dodge JL, Gunderson EP, Rubin J, Irani RA, Cedars M, Terrault N. Non-alcoholic fatty liver disease in pregnancy is associated with adverse maternal and perinatal outcomes. J Hepatol. 2020 Apr 15:S0168-8278(20)30215-4. Epub ahead of print. PMID:32531415.

Qin Y, Ting F, Kim MJ, Strelnikov J, Harmon J, Gao F, Dose A, Teng BB, Alipour MA, Yao Z, Crooke R, Krauss RM, Medina MW. Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation. Arterioscler Thromb Vasc Biol. 2020 May;40(5):1311-1324. PMID:32188273; PMCID:PMC7197750.

Ibars M, Maier MT, Yulyaningsih E, Perez L, Cheang R, Vilhelmsson A, Louie SM, Wegner SA, Yuan X, Eltzschig HK, Hopf FW, Nomura DK, Koliwad SK, Xu AW.
Neuronal modulation of hepatic lipid accumulation induced by bingelike drinking. Am J Physiol Endocrinol Metab. 2020 May 1;318(5):E655-E666. PMID:32045262; PMCID:PMC7272724.