Member Publications

Alexander M, Upadhyay V, Rock R, Ramirez L, Trepka K, Puchalska P, Orellana D, Ang QY, Whitty C, Turnbaugh JA, Tian Y, Dumlao D, Nayak R, Patterson A, Newman JC, Crawford PA, Turnbaugh PJ. A diet-dependent host metabolite shapes the gut microbiota to protect from autoimmunity. Cell Rep. 2024 Oct 18:114891. doi: 10.1016/j.celrep.2024.114891. Epub ahead of print. PMID: 39500329.

Babdor J, Patel RK, Davidson B, Noecker C, Rahim M, Bisanz JE, Tenvooren I, Marquez D, Calvo M, Johri V, McCarthy E, Shaheed A, Ekstrand C, Weakley AM, Yu FB, Fiehn O, Turnbaugh PJ, Combes AJ, Fragiadakis GK, Spitzer MH. Coordinated variation in the immune systems and microbiomes of healthy humans is linked to tonic interferon states. bioRxiv [Preprint]. 2024 Dec 3:2024. 11.27.625750. doi: 10.1101/2024.11.27.625750. PMID: 39677657; PMCID: PMC11642739.

Bae M, Le C, Mehta RS, Dong X, Pieper LM, Ramirez L, Alexander M, Kiamehr S, Turnbaugh PJ, Huttenhower C, Chan AT, Balskus EP. Metatranscriptomics-guided discovery and characterization of a polyphenol-metabolizing gut microbial enzyme. Cell Host Microbe. 2024 Nov 13;32(11):1887-1896.e8. doi:10.1016/j.chom.2024.10.002. Epub 2024 Oct 28. PMID: 39471822.

Bhasuran B, Schmolly K, Kapoor Y, Jayakumar NL, Doan R, Amin J, Meninger S, Cheng N, Deering R, Anderson K, Beaven SW, Wang B, Rudrapatna VA. Reducing diagnostic delays in acute hepatic porphyria using health records data and machine learning. J Am Med Inform Assoc. 2025 Jan 1;32(1):63-70. doi: 10.1093/jamia/ocae141. PMID: 38946554; PMCID: PMC11648717.

Bruno BJ, Weavil JC, Ogle J, Chidambaram N, Carey EJ, Danford CJ, Fricker ZP, Galati JS, Lee WM, Mantry PS, Shetty K, DelConte A, Patel MV, Lai JC, Sanyal AJ. Oral LPCN 1148 improves sarcopenia and hepatic encephalopathy in male patients with cirrhosis: A randomized, placebo-controlled phase 2 trial. Hepatology. 2024 Nov 8. doi: 10.1097/HEP.0000000000001146. Epub ahead of print. PMID: 39513970.

Chang CW, Chen YS, Huang CH, Lin CH, Ng WV, Chu LJ, Trépo E, Zucman-Rossi J, Siao K, Maher JJ, Chiew MY, Chou CH, Huang HD, Teo WH, Lee IS, Lo JF, Wang XW. A genetic basis of mitochondrial DNAJA3 in nonalcoholic steatohepatitis-related hepatocellular carcinoma. Hepatology. 2025 Jan 1;81(1):60-76. doi: 10.1097/HEP.0000000000000637. Epub 2023 Oct 23. PMID: 37870291; PMCID: PMC11035488.

Cullaro G, Allegretti AS, Fenton C, Ge J, Patidar KR, Rubin J, Sharma A, Lai JC. The association between mean arterial pressure and acute kidney injury reversal among patients with decompensated cirrhosis. Hepatology. 2025 Jan 1;81(1):126-135. doi: 10.1097/HEP.0000000000000858. Epub 2024 Mar 27. PMID: 38537129; PMCID: PMC11427603.

Cullaro G, Allegretti AS, Patidar KR, Verna EC, Lai JC. Cystatin C and the difference between cystatin C and serum creatinine: Improved metrics to predict waitlist mortality among patients with decompensated cirrhosis. Liver Transpl. 2025 Jan 1;31(1):24-31. doi: 10.1097/LVT.0000000000000439. Epub 2024 Jul 24. PMID: 39041923.

Dixon W, Feng S, Roll GR, Tavakol M, Fenton C, Cullaro G. The type, duration, and severity of pretransplant kidney injury predict prolonged kidney dysfunction after liver transplantation. Liver Transpl. 2024 Nov 1;30(11):1159-1168. doi: 10.1097/LVT.0000000000000386. Epub 2024 May 28. PMID: 38982612.

Hillege LE, Trepka KR, Ziemons J, Aarnoutse R, Guthrie BGH, de Vos-Geelen J, Valkenburg-van Iersel L, van Hellemond IEG, Baars A, Vestjens JHMJ, Penders J, Deutschbauer A, Atreya CE, Kidder WA, Turnbaugh PJ, Smidt ML. Metagenomic analysis during capecitabine therapy reveals microbial chemoprotective mechanisms and predicts drug toxicity in colorectal cancer patients. medRxiv [Preprint]. 2024 Oct 15:2024.10.11.24315249. doi: 10.1101/2024.10.11.24315249. PMID: 39484258; PMCID: PMC11527039.

Hung P, Yu J, Harrison SE, Liu J, Promiti A, Odahowski C, Campbell BA, Chatterjee A, Boghoossian NS, Cai B, Liang C, Li J, Li X; National COVID Cohort Collaborative Consortium (Ge J). Racial and Ethnic and Rural Variations in the Use of Hybrid Prenatal Care in the US. JAMA Netw Open. 2024 Dec 2;7(12):e2449243. doi:10.1001/jamanetworkopen.2024.49243. PMID: 39641928; PMCID: PMC11624583.

Hwang SY, Danpanichkul P, Agopian V, Mehta N, Parikh ND, Abou-Alfa GK, Singal AG, Yang JD. Hepatocellular carcinoma: updates on epidemiology, surveillance, diagnosis and treatment. Clin Mol Hepatol. 2024 Dec 26. doi: 10.3350/cmh.2024.0824. Epub ahead of print. PMID: 39722614.

Jain A, Heremans I, Rademaker G, Detomasi TC, Hernandez GA, Zhang J, Gupta S, von Linde T, Lange M, Spacci M, Rohweder P, Anderson D, Citron YR, Olzmann JA, Dawson DW, Craik CS, Bommer G, Perera RM, Zoncu R. Leucine Aminopeptidase LyLAP enables lysosomal degradation of membrane proteins. bioRxiv [Preprint]. 2024 Dec 14:2024.12.13.628212. doi: 10.1101/2024.12.13.628212. PMID: 39713462; PMCID: PMC11661280.

Kone LB, Seok D, Kimble MM, Maker AV, Patil S, Mittal V, Jacobs M. ASO Visual Abstract: Essential Elements in Synoptic Operative Reports for Hepato-Pancreato-Biliary Cancer Surgery-An HPB/CGSO Training Program Survey. Ann Surg Oncol. 2024 Dec 2. doi: 10.1245/s10434-024-16560-7. Epub ahead of print. PMID: 39623185.

Kone LB, Seok D, Kimble MM, Maker AV, Patil S, Mittal V, Jacobs M. Essential Elements in Synoptic Operative Reports for Hepato-Pancreato-Biliary Cancer Surgery: An HPB/CGSO Training Program Survey. Ann Surg Oncol. 2025 Jan;32(1):382-390. doi: 10.1245/s10434-024-16276-8. Epub 2024 Sep 30. PMID: 39349910.

Lai JC, Sarin SK, Gines P. From prognostication to therapeutics: Four key questions to accelerate the development of therapeutics for patients with acute-on-chronic liver failure. Am J Transplant. 2024 Nov;24(11):1963-1967. doi: 10.1016/j.ajt.2024.06.007. Epub 2024 Jul 22. PMID: 39047977.

Li X, Ouyang T, Belcher JM, Patidar KR, Cullaro G, Asrani SK, Wadei HM, Simonetto DA, Regner KR, Dageforde LA, Przybyszewski EM, Wilechansky RM, Sharma P, Ufere NN, Duarte-Rojo A, Wahid NA, Orman ES, St Hillien SA, Robinson JE, Chung RT, Allegretti AS; I on behalf of the HRS-HARMONY research collaborative. Impact of acute kidney injury response on survival and liver transplant rates in hospitalized patients with cirrhosis awaiting liver transplantation: Results from the HRS-HARMONY consortium. Liver Transpl. 2024 Nov 1;30(11):1106-1115. doi: 10.1097/LVT.0000000000000445. Epub 2024 Jul 30. PMID: 39073567.

Luk JW, Ha NB, Shui AM, Snyder HR, Batki SL, Ostacher MJ, Monto A, Wong RJ, Cheung R, Parekh P, Hua W, Tompkins DA, Fakadej T, Haight CG, Liao M, Khalili M, Satre DD. Demographic and clinical characteristics associated with utilization of alcohol use disorder treatment in a multicenter study of patients with alcohol-associated cirrhosis. Alcohol Clin Exp Res (Hoboken). 2024 Dec 4. doi: 10.1111/acer.15500. Epub ahead of print. PMID: 39632077.

Luo Y, Fraser L, Jezykowski J, Gupta NA, Miethke AG, Taylor SA, Alonso EM, Horslen S, Kohli R, Molleston JP, Kamath BM, Guthery SL, Loomes KM, Magee JC, Rosenthal P, Valentino P, Sokol RJ, Mack CL; Childhood Liver Disease Research Network. Interleukin 8-CXCR2 mediated neutrophil extracellular trap (NET) formation in biliary atresia associated with NET-Induced stellate cell activation. Hepatology. 2024 Dec 18. doi: 10.1097/HEP.0000000000001195. Epub ahead of print. PMID: 39693274.

Moya-Garzon MD, Wang M, Li VL, Lyu X, Wei W, Tung AS, Raun SH, Zhao M, Coassolo L, Islam H, Oliveira B, Dai Y, Spaas J, Delgado-Gonzalez A, Donoso K, Alvarez-Buylla A, Franco-Montalban F, Letian A, Ward CP, Liu L, Svensson KJ, Goldberg EL, Gardner CD, Little JP, Banik SM, Xu Y, Long JZ. A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites. Cell. 2024 Nov 7:S0092-8674(24)01214-5. doi: 10.1016/j.cell.2024.10.032. Epub ahead of print. PMID: 39536746.

Norman J, Mehta N, Kim WR, Liang JW, Biggins SW, Asrani SK, Heimbach J, CharucV, Kwong AJ. Multi-HCC: A practical model to prioritize patients withchepatocellular carcinoma on the liver transplant waiting list. Gastroenterology. 2024 Nov 30:S0016-5085(24)05754-8. doi: 10.1053/j.gastro.2024.11.015. Epub ahead of print. PMID: 39622302.

Norman JS, Li PJ, Kotwani P, Yao FY, Pham S, Gamez J, Mehta N. Enhancing the prognostic accuracy of the RETREAT score with AFP-L3 and DCP tumor markers. Liver Transpl. 2024 Dec 12. doi: 10.1097/LVT.0000000000000551. Epub ahead of print. PMID: 39661334.

Patel S, Khalili M, Singal AG, Pinheiro PS, Jones PD, Kim RG, Kode V, Thiemann A, Zhang W, Cheung R, Wong RJ. Significant Disparities in Hepatocellular Carcinoma Outcomes by Race/Ethnicity and Sociodemographic Factors. Cancer Epidemiol Biomarkers Prev. 2024 Dec 5. doi:10.1158/1055-9965.EPI-24-1094. Epub ahead of print. PMID: 39636161.

Rajagopal S, Ritchie J, Seidman D, Perito ER, Adey D, Sarkar M. Family Planning Counseling and Practices in Kidney Transplant Recipients. Clin Transplant. 2024 Dec;38(12):e70047. doi: 10.1111/ctr.70047. PMID: 39624937.

Rezaee-Zavareh MS, Yeo YH, Wang T, Guo Z, Tabrizian P, Ward SC, Barakat F, Hassanein TI, Dave S, Ajmera V, Bhoori S, Mazzaferro V, Chascsa DMH, Liu MC, Aby ES, Lake JR, Sogbe M, Sangro B, Abdelrahim M, Esmail A, Schmiderer A, Chouik Y, Rudolph M, Sohal D, Giudicelli H, Allaire M, Akce M, Guadagno J, Tow CY, Massoumi H, De Simone P, Kang E, Gartrell RD, Martinez M, Paz-Fumagalli R, Toskich BB, Tran NH, Solino GA, Poltronieri Pacheco DM, Kalman RS, Agopian VG, Mehta N, Parikh ND, Singal AG, Yang JD. Impact of pre-transplant immune checkpoint inhibitor use on post-transplant outcomes in HCC: A systematic review and individual patient data meta-analysis. J Hepatol. 2025 Jan;82(1):107-119. doi: 10.1016/j.jhep.2024.06.042. Epub 2024 Jul 10. PMID: 38996924; PMCID: PMC11655254.

Salem R, Kwong AJ, Kim N, Sze DY, Mehta N. YTTRIUM-90 RADIOEMBOLIZATION HAS BECOME THE MOST UTILIZED BRIDGING TREATMENT FOR LIVER TRANSPLANT CANDIDATES IN THE UNITED STATES. J Vasc Interv Radiol. 2024 Nov 8:S1051-0443(24)00694-8. doi: 10.1016/j.jvir.2024.10.034. Epub ahead of print. PMID: 39522866.

Samala N, Xin Y, Wilson LA, Yates K, Loomba R, Hoofnagle JH, Chalasani N; NASH Clinical Research Network. Non-Hispanic Black Persons With Nonalcoholic Fatty Liver Disease Have Lower Rates of Advanced Fibrosis, Cirrhosis, and Liver-Related Events Even After Controlling for Clinical Risk Factors and PNPLA3 Genotype (Hameed B). Am J Gastroenterol. 2024 Sep 1;119(9):1857-1865. doi: 10.14309/ajg.0000000000002756. Epub 2024 May 14. PMID: 38483303; PMCID: PMC11399313.

Satre DD, Dasarathy D, Batki SL, Ostacher MJ, Snyder HR, Hua W, Parekh P, Shui AM, Cheung R, Monto A, Wong RJ, Chen JY, Liao M, Tana M, Chen PH, Haight CG, Fakadej T, Khalili M. Factors Associated With Motivation to Reduce Alcohol Use Among Patients With Chronic Liver Disease. Aliment Pharmacol Ther. 2024 Nov 11. doi: 10.1111/apt.18387. Epub ahead of print. PMID: 39523996.

Singal AG, Quirk L, Boike J, Chernyak V, Feng Z, Giamarqo G, Kanwal F, Ioannou GN, Manes S, Marrero JA, Mehta N, Pillai A, Shaheen NJ, Shaukat A, Sirlin CB, Verna E, Wani S, Wilson Woods A, Yang JD, Parikh ND. Value of HCC surveillance in a landscape of emerging surveillance options: Perspectives of a multi-stakeholder modified delphi panel. Hepatology. 2024 Dec 18. doi: 10.1097/HEP.0000000000001203. Epub ahead of print. PMID: 39699563.

Squires JE, Perito ER, Garza A, Urban R, Soltys KA, Pahl E, Krise-Confair C, Mazariegos GV. Development of a collaborative learning health system data mart in pediatric Liver Transplantation. Liver Transpl. 2024 Dec 11. doi: 10.1097/LVT.0000000000000552. Epub ahead of print. PMID: 39665642.

St Hillien SA, Robinson JE, Ouyang T, Patidar KR, Belcher JM, Cullaro G, Regner KR, Chung RT, Ufere N, Velez JCQ, Neyra JA, Asrani SK, Wadei H, Teixeira JP, Saly DL, Levitsky J, Orman E, Sawinski D, Dageforde LA, Allegretti AS; HRS-HARMONY Consortium. Acute Kidney Injury in Patients with Cirrhosis and Chronic Kidney Disease: Results from the HRS-HARMONY Consortium. Clin Gastroenterol Hepatol. 2024 Dec 13:S1542-3565(24)01074-7. doi: 10.1016/j.cgh.2024.10.023. Epub ahead of print. PMID: 39675402.

Turnham RE, Pitea A, Jang GM, Xu Z, Lim HC, Choi AL, Von Dollen J, Levin RS, Webber JT, McCarthy E, Hu J, Li X, Che L, Singh A, Yoon A, Chan G, Kelley RK, Swaney DL, Zhang W, Bandyopadhyay S, Theis FJ, Eckhardt M, Chen X, Shokat KM, Ideker T, Krogan NJ, Gordan JD. HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma. Cancer Res. 2024 Dec 9. doi: 10.1158/0008-5472.CAN-24-0456. Epub ahead of print. PMID: 39652575.

Wadhwani SI, Squires JE, Hsu E, Gupta N, Campbell K, Zielsdorf S, Vittorio J, Desai DM, Ebel NH, Shui AM, Bucuvalas JC, Gottlieb LM, Lyles CR, Lai JC; Society of Pediatric Liver Transplantation. Material economic hardship is associated with adverse 1-year outcomes after pediatric liver transplantation: Prospective cohort results from the multi-center SOCIAL-Tx study. Liver Transpl. 2024 Dec 16. doi: 10.1097/LVT.0000000000000554. Epub ahead of print. PMID: 39692470.

Wang WK, Jeong H, Hershkovich L, Cho P, Singh K, Lederer L, Roghanizad AR, Shandhi MMH, Kibbe W, Dunn J; National COVID Cohort Collaborative (N3C) Consortium (Ge J). Tree-based classification model for Long-COVID infection prediction with age stratification using data from the National COVID Cohort Collaborative. JAMIA Open. 2024 Oct 9;7(4):ooae111. doi: 10.1093/jamiaopen/ooae111. PMID: 39524607; PMCID: PMC11547948.

Zhang GY, Cortella A, Lai JC, Rubin JB. Pain in chronic liver disease compared to other chronic conditions: Results from a contemporary nationally representative cohort study. Hepatol Commun. 2024 Dec 11;9(1):e0605. doi: 10.1097/HC9.0000000000000605. PMID: 39670874; PMCID: PMC11637743.

Zhou K, Nguyen L, Tabrizian P, Mehta N. Sociodemographic disparities in downstaging to liver transplant for hepatocellular carcinoma. Liver Transpl. 2024 Nov 8. doi: 10.1097/LVT.0000000000000532. Epub ahead of print. PMID: 39508738.

Zhou Y, Zhang S, Qiu G, Wang X, Yonemura A, Xu H, Cui G, Deng S, Chun J, Chen N, Xu M, Song X, Wang J, Xu Z, Deng Y, Evert M, Calvisi DF, Lin S, Wang H, Chen X. TSC/mTORC1 mediates mTORC2/AKT1 signaling in c-MYC-induced murine hepatocarcinogenesis via centromere protein M. J Clin Invest. 2024 Sep 26;134(22):e174415. doi: 10.1172/JCI174415. PMID: 39325536; PMCID: PMC11563669.