Liver-related member publications appearing in PubMed in March 2025*
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* Some publications in this list appeared initially in PubMed much earlier, and now are in their final print versions. For a full list of 2024 publications, use the link in the left banner.
Center members in BOLD; T32 trainees in italics
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Agarwal V, Inoue F, Schubach M, Penzar D, Martin BK, Dash PM, Keukeleire P, Zhang Z, Sohota A, Zhao J, Georgakopoulos-Soares I, Noble WS, Yardımcı GG, Kulakovskiy IV, Kircher M, Shendure J, Ahituv N. Massively parallel characterization of transcriptional regulatory elements. Nature. 2025 Mar;639(8054):411-420. doi: 10.1038/s41586-024-08430-9. Epub 2025 Jan 15. PMID: 39814889; PMCID: PMC11903340. |
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Ahituv N. 2024 ASHG Sc ientific Achievement Award. Am J Hum Genet. 2025 Mar 6;112(3):473-477. doi: 10.1016/j.ajhg.2025.01.005. PMID: 40054438. |
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Benet LZ, Sodhi JK, Tiitto MV, Xiang Y. Application of Kirchhoff's Laws to pharmacologic and pharmacokinetic analyses. Pharmacol Rev. 2025 Mar 21;77(3):100050. doi: 10.1016/j.pharmr.2025.100050. Epub ahead of print. PMID: 40120204. |
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Benet LZ, Sodhi JK. Response to the commentary on "Are all measures of liver Kp<sub>uu</sub> a function of F<sub>H</sub>, as determined following oral dosing, or have we made a critical error in defining hepatic drug clearance?". Eur J Pharm Sci. 2025 Mar 31:107088. doi: 10.1016/j.ejps.2025.107088. Epub ahead of print. PMID: 40174658. |
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Cullaro G, Allegretti AS, Patidar KR, Jamil K, Velez JCQ. The relationship between mean arterial pressure and terlipressin in hepatorenal syndrome-acute kidney injury reversal: a post hoc analysis. Hepatology. 2025 Mar 7. doi: 10.1097/HEP.0000000000001295. Epub ahead of print. PMID: 40053863. |
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Ge J, Fontil V, Ackerman S, Pletcher MJ, Lai JC. Clinical decision support and electronic interventions to improve care quality in chronic liver diseases and cirrhosis. Hepatology. 2025 Apr 1;81(4):1353-1364. doi: 10.1097/HEP.0000000000000583. Epub 2023 Aug 23. PMID: 37611253; PMCID: PMC10998693. |
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Gonzalez-Peralta RP, Wen JW, Hardikar W, Karnsakul WW, Whitworth S, Lin CH, Indolfi G, Rosenthal P, Balistreri W, Schwarz KB, Honegger JR, Zhang X, Svarovskaia EC, Suri V, Kersey K, Leung DH. Long-term efficacy and safety of sofosbuvir-based direct-acting antiviral regimens in paediatric patients with hepatitis C virus infection: an international registry study. Lancet Child Adolesc Health. 2025 Apr;9(4):248-254. doi: 10.1016/S2352-4642(25)00028-8. PMID:40113366 |
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Ha NB, Heimbach JK, Hameed B. Optimizing liver transplant candidacy in patients with cirrhosis and obesity. Liver Transpl. 2025 Mar 25. doi: 10.1097/LVT.0000000000000609. Epub ahead of print. PMID: 40131000. |
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Haldar T, Kvale M, Yang J, Douglas MP, Coyote-Maetas W, Kachuri L, Witte JS, Iribarren C, Medina MW, Krauss RM, Yee SW, Oni-Orisan A. SLCO1B1 Functional Variants, Bilirubin, Statin-Induced Myotoxicity, and Recent Sub-Saharan African Ancestry: A Precision Medicine Health Equity Study. Clin Pharmacol Ther. 2025 Mar 6. doi: 10.1002/cpt.3624. Epub ahead of print. PMID: 40047317. |
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Hwang SY, Danpanichkul P, Agopian V, Mehta N, Parikh ND, Abou-Alfa GK, Singal AG, Yang JD. Hepatocellular carcinoma: updates on epidemiology, surveillance, diagnosis and treatment. Clin Mol Hepatol. 2025 Feb;31(Suppl):S228-S254. doi: 10.3350/cmh.2024.0824. Epub 2024 Dec 26. PMID: 39722614; PMCID: PMC11925437. |
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Jain A, Heremans I, Rademaker G, Detomasi TC, Rohweder P, Anderson D, Zhang J, Hernandez GA, Gupta S, von Linde T, Lange M, Spacci M, Luo J, Citron YR, Olzmann JA, Dawson DW, Craik CS, Bommer G, Perera RM, Zoncu R. Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins. Science. 2025 Mar 28;387(6741):eadq8331. doi: 10.1126/science.adq8331. Epub 2025 Mar 28. PMID: 40146846. |
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Katz-Greenberg G, Afshar Y, Bonn J, Casale J, Constantinescu S, DeFilippis EM, George RP, Iltis A, Jesudason S, Kittleson M, Levine DJ, Moritz MJ, Sarkar M, Shah S, Uccellini K, Coscia LA, Rossi AP; American Society of Transplantation Women’s Health Community of Practice Reproductive Health, Contraception and Pregnancy after Transplantation and Living Donation Controversies Conference Participants. Pregnancy After Solid Organ Transplantation: Review of the Evidence and Recommendations. Transplantation. 2025 Mar 13. doi: 10.1097/TP.0000000000005341. Epub ahead of print. PMID: 40074722. |
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Kim Y, Nickles TM, Lee PM, Bok RA, Gordon JW, Larson PEZ, Vigneron DB, von Morze C, Ohliger MA. A data-driven approach for improved quantification of in vivo metabolic conversion rates of hyperpolarized [1-<sup>13</sup>C]pyruvate. Magn Reson Med. 2025 Jun;93(6):2346-2356. doi: 10.1002/mrm.30445. Epub 2025 Feb 18. PMID: 39963732; PMCID: PMC11971488. |
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Kjaergaard U, Lund A, Redda M, Kristensen MH, Aastrup M, Bøgh N, Sivesgaard K, Ohliger MA, Vigneron DB, Bertelsen LB, Alstrup AKO, Hansen ESS, Mortensen FV, Laustsen C. Regional quantification of metabolic liver function using hyperpolarized [1-<sup>13</sup>C] pyruvate MRI. Sci Rep. 2025 Mar 26;15(1):10482. doi: 10.1038/s41598-025-93725-8. PMID: 40140493; PMCID: PMC11947255. |
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Kuang YL, Locatelli CAA, Qin Y, Zhang Y, Theusch E, Muñoz-Howell A, Sanchez G, Lu M, Nguyen MA, Yalamanchili T, Wang X, Nalula G, Mattis AN, Oni-Orisan A, Iribarren C, Krauss RM, Mulvihill EE, Medina MW. <i>MIR192</i> Upregulates GLP-1 Receptor and Improves Statin-Induced Impairment of Insulin Secretion. bioRxiv [Preprint]. 2025 Mar 19:2025.03.18.643960. doi: 10.1101/2025.03.18.643960. PMID: 40166140; PMCID: PMC11956930. |
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Lai JC, Shui AM, Molinari M, Rahimi R, Ladner D, Ganger D, Kappus M, King E, Tevar A, Volk M, Duarte-Rojo A, Verna EC. The Liver Transplant Comorbidity Index (LTCI) : A composite index of ambulatory Pre-LT factors to identify patients at increased risk of Post-LT Mortality. Hepatology. 2025 Mar 25. doi: 10.1097/HEP.0000000000001320. Epub ahead of print. PMID: 40132167. |
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Li PJ, Tabrizian P, Daher D, Gaviria F, Ajmera V, Montalvan-Sanchez EE, Gutierrez JA, Zhou K, Delebecque F, Garcia N, Barrick B, Wong C, Nephew L, Holden J, Dave S, Schnickel GT, Rich NE, Florman SS, Sapisochin G, Yao F, Singal AG, Mehta N. A prospective multicenter validation of RETREAT for post-transplantation hepatocellular carcinoma recurrence prediction. Hepatology. 2025 Mar 11. doi: 10.1097/HEP.0000000000001297. Epub ahead of print. PMID: 40067686. |
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Miller PN, Baskaran S, Nijagal A. Immunology of Biliary Atresia. Semin Pediatr Surg. 2024 Dec;33(6):151474. doi: 10.1016/j.sempedsurg.2025.151474. Epub 2025 Jan 18. PMID: 39862687. |
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Nobel YR, Boike JR, Mazumder NR, Thornburg B, Hoffman R, Kolli KP, Fallon M, Lai JC, Morelli G, Spengler EK, Said A, Desai AP, Paul S, Goel A, Hu K, Frenette C, Gregory D, Padilla C, Zhang Y, VanWagner LB, Verna EC; Advancing Liver Therapeutic Approaches (ALTA) Study Group. Predictors of long-term clinical outcomes after TIPS: An ALTA group study. Hepatology. 2025 Apr 1;81(4):1244-1255. doi: 10.1097/HEP.0000000000001091. Epub 2024 Sep 10. PMID: 39255519. |
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Norman JS, Mehta N, Kim WR, Liang JW, Biggins SW, Asrani SK, Heimbach J, Charu V, Kwong AJ. Model of Urgency for Liver Transplantation in Hepatocellular Carcinoma: A Practical Model to Prioritize Patien: ts With Hepatocellular Carcinoma on the Liver Transplant Waitlist. Gastroenterology. 2025 Apr;168(4):784-794.e4. doi: 10.1053/j.gastro.2024.11.015. Epub 2024 Nov 30. PMID 39622302; PMCID: PMC11930618. |
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Tapper EB, Goldberg D, Parikh ND, Terrault NA, Welch N, Sharpton S, Hameed B, Khalili M, Stolz A, Verna EC, Brown RS Jr, Sanyal AJ, VanWagner L, Ladner DP, Moylan CA, Diehl AM, Jones PD, Loomba R, Dasarathy S, Simonetto DA, Shah VH, Bajaj JS; LCN Study Group. The Liver Cirrhosis Network Cohort Study: Cirrhosis Definition, Study Population, and Endpoints. Am J Gastroenterol. 2025 Mar 1;120(3):570-575. doi: 10.14309/ajg.0000000000002953. Epub 2024 Jul 17. PMID: 39018024; PMCID: PMC11739427. |
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Tsusaka T, Najar MA, Schwarz B, Bohrnsen E, Oses-Prieto JA, Neudorf H, Lee C, Little JP, Burlingame AL, Bosio CM, Burslem GM, Goldberg EL. Reversible histone deacetylase activity catalyzes lysine acylation. Nat Chem Biol. 2025 Mar 26. doi: 10.1038/s41589-025-01869-5. Epub ahead of print. PMID: 40140626. |
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Tsusaka T, Najar MA, Sharma I, Marcinkiewicz MM, Crispim CVDS, Snyder NW, Burslem GM, Goldberg EL. Class I histone deacetylases catalyze lysine lactylation. bioRxiv [Preprint]. 2025 Feb 28:2025.02.25.640220. doi: 10.1101/2025.02.25.640220. PMID: 40060688; PMCID: PMC11888385. |
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Ufere NN, Zeng C, Donlan J, Shalev D, Kaplan A, Noll A, Liu A, Pintro K, Horick N, Indriolo T, Li L, Zhu E, Armstrong ME, Mason N, Engel KG, Rowland M, O'Brien K, Kenimer S, Diop MS, Jackson V, Lai JC, Chung RT, Jacobs JM, Edelen MO, El-Jawahri A. Psychological Distress Is Prevalent and Interdependent Among Patients With Decompensated Cirrhosis and Their Caregivers. Am J Gastroenterol. 2025 Apr 1;120(4):909-913. doi: 10.14309/ajg.0000000000003158. Epub 2024 Oct 25. PMID: 39450861. |
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Valdearcos M, McGrath ER, Brown Mayfield SM, Jacuinde MG, Folick A, Cheang RT, Li R, Bachor TP, Lippert RN, Xu AW, Koliwad SK. Microglia mediate the early-life programming of adult glucose control. Cell Rep. 2025 Mar 25;44(3):115409. doi: 10.1016/j.celrep.2025.115409. Epub 2025 Mar 12. PMID: 40085644 |
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Wang M, Chiou SH, Ganger D, Ruck J, Huang CY, Kappus MR, King EA, Ladner DP, Rahimi RS, Duarte-Rojo A, Volk ML, Tevar AD, Verna EC, Lai JC. Liver transplantation provides survival benefit at all levels of frailty: From the Multicenter Functional Assessment in Liver Transplantation Study. Hepatology. 2025 Apr 1;81(4):1269-1275. doi: 10.1097/HEP.0000000000001030. Epub 2024 Jul 24. PMID: 39047086; PMCID: PMC11757801. |
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Wang M, Harris A, McCulloch CE, Wadhwani SI, Lai JC, Rubin JB. Racial differences in primary sclerosing cholangitis: A retrospective cohort study leveraging a new ICD-10 code. Ann Hepatol. 2025 Mar 11:101901. doi: 10.1016/j.aohep.2025.101901. Epub ahead of print. PMID: 40081809. |
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Wang M, Jutras G, Cullaro G, Dhruva A, Lai JC. Patterns of dietary supplement use among United States patients with steatotic liver disease: Vitamins, minerals and botanicals. World J Hepatol. 2025 Mar 27;17(3):103537. doi: 10.4254/wjh.v17.i3.103537. PMID: 40177193; PMCID: PMC11959662. |
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Xu E, Mehta N. Reply: Downstaging of hepatocellular carcinoma before liver transplantation. Hepatology. 2025 Mar 10. doi: 10.1097/HEP.0000000000001303. Epub ahead of print. PMID: 40067684. |
