Liver Center Member Publications

Member publications appearing in PubMed April-June 2017 *

* Liver-related publications only


Chan R, Benet LZ. Evaluation of DILI Predictive Hypotheses in Early Drug Development. Chem Res Toxicol. 2017 Apr 17;30(4):1017-1029. doi:10.1021/acs.chemrestox.7b00025. Epub 2017 Mar 15. PubMed

Chen EC, Khuri N, Liang X, Stecula A, Chien HC, Yee SW, Huang Y, Sali A, Giacomini KM. Discovery of Competitive and Noncompetitive Ligands of the Organic  Cation Transporter 1 (OCT1; SLC22A1). J Med Chem. 2017 Apr 13;60(7):2685-2696. doi: 10.1021/acs.jmedchem.6b01317. Epub 2017 Mar 15. PubMed

Cigliano A, Wang C, Pilo MG, Szydlowska M, Brozzetti S, Latte G, Pes GM, Pascale RM, Seddaiu MA, Vidili G, Ribback S, Dombrowski F, Evert M, Chen X, Calvisi DF. Inhibition of HSF1 suppresses the growth of hepatocarcinoma cell lines in vitro and AKT-driven hepatocarcinogenesis in mice. Oncotarget. 2017 Apr 7. doi: 10.18632/oncotarget.16927. [Epub ahead of print] PubMed

Duwaerts CC, Amin AM, Siao K, Her C, Fitch M, Beysen C, Turner SM, Goodsell A, Baron JL, Grenert JP, Cho SJ, Maher JJ. Specific Macronutrients Exert Unique Influences on the Adipose-Liver Axis to Promote Hepatic Steatosis in Mice. Cell Mol Gastroenterol Hepatol. 2017 Apr 22;4(2):223-236. doi: 10.1016/j.jcmgh.2017.04.004. eCollection 2017 Sep. PubMed

Lai JC, Covinsky KE, Dodge JL, Boscardin WJ, Segev DL, Roberts JP, Feng S. Development of a Novel Frailty Index to Predict Mortality in Patients with End-Stage Liver Disease. Hepatology. 2017 Apr 19. doi: 10.1002/hep.29219. [Epub ahead of print] PubMed

Loskill P, Sezhian T, Tharp KM, Lee-Montiel FT, Jeeawoody S, Reese WM, Zushin  PH, Stahl A, Healy KE. WAT-on-a-chip: a physiologically relevant microfluidic system incorporating white adipose tissue. Lab Chip. 2017 Apr 18. doi: 10.1039/c6lc01590e. [Epub ahead of print] PubMed

Marco-Rius I, Gordon JW, Mattis AN, Bok R, Delos Santos R, Sukumar S, Larson PEZ, Vigneron DB, Ohliger MA. Diffusion-weighted imaging of hyperpolarized [(13) C]urea in mouse liver. J Magn Reson Imaging. 2017 Apr 17. doi: 10.1002/jmri.25721. [Epub ahead of print] PubMed

Mehta N, Heimbach J, Harnois DM, Sapisochin G, Dodge JL, Lee D, Burns JM, Sanchez W, Greig PD, Grant DR, Roberts JP, Yao FY. Validation of a Risk Estimation of Tumor Recurrence After Transplant (RETREAT) Score for Hepatocellular Carcinoma Recurrence After Liver Transplant. JAMA Oncol. 2017 Apr 1;3(4):493-500. doi: 10.1001/jamaoncol.2016.5116. PubMed

Naggie S, Marks KM, Hughes M, Fierer DS, Macbrayne C, Kim A, Hollabaugh K, Roa J, Symonds B, Brainard DM, McHutchison JG, Peters MG, Kiser JJ, Chung R; AIDS Clinical Trials Group (ACTG) A5327 Study Team. Sofosbuvir Plus Ribavirin Without Interferon for Treatment of Acute Hepatitis C Virus Infection in HIV-1-Infected Individuals: SWIFT-C. Clin Infect Dis. 2017 Apr 15;64(8):1035-1042. doi: 10.1093/cid/cix025. PubMed

Perito ER, Vase T, Ramachandran R, Phelps A, Jen KY, Lustig RH, Feldstein VA,  Rosenthal P. Hepatic steatosis after pediatric liver transplant. Liver Transpl. 2017 Apr 20. doi: 10.1002/lt.24773. [Epub ahead of print] PubMed

Wilson DM, Di Gialleonardo V, Wang ZJ, Carroll V, Von Morze C, Taylor A, Sai V, VanCriekinge M, Bok R, Ohliger MA, Keshari KR. Hyperpolarized (13)C Spectroscopic Evaluation of Oxidative Stress in a Rodent Model of Steatohepatitis. Sci Rep. 2017 Apr 20;7:46014. doi: 10.1038/srep46014. PubMed

Wu CS, Bongmba OYN, Yue J, Lee JH, Lin L, Saito K, Pradhan G, Li DP, Pan HL, Xu A, Guo S, Xu Y, Sun Y. Suppression of GHS-R in AgRP Neurons Mitigates Diet-Induced Obesity by Activating Thermogenesis. Int J Mol Sci. 2017 Apr 14;18(4). pii: E832. doi: 10.3390/ijms18040832. PubMed

Wu HF, Hristeva N, Chang J, Liang X, Li R, Frassetto L, Benet LZ. Rosuvastatin Pharmacokinetics in Asian and White Subjects wild-type for Both OATP1B1 and BCRP Under Control and Inhibited Conditions. J Pharm Sci. 2017 Apr 3. pii: S0022-3549(17)30213-7. doi: 10.1016/j.xphs.2017.03.027. [Epub ahead of print] PubMed


Benet LZ, Wu HF. Understanding the Potential Interethnic Difference in Rosuvastatin Pharmacokinetics. J Pharm Sci. 2017 May 11. pii: S0022-3549(17)30362-3. doi: 10.1016/j.xphs.2017.05.008. [Epub ahead of print] PubMed

Cai L, Yeh BM, Westphalen AC, Roberts JP, Wang ZJ. Adult living donor liver imaging. Diagn Interv Radiol. 2016 May-Jun;22(3):207-14. doi: 10.5152/dir.2016.15323. PubMed

Ganeshan K, Chawla A. Warming the mouse to model human diseases. Nat Rev Endocrinol. 2017 May 12. doi: 10.1038/nrendo.2017.48. [Epub ahead of print] Review. PubMed

Ge J, Roberts JP, Lai JC. Race/Ethnicity is Associated with ABO Non-Identical Liver Transplantation in the United States. Clin Transplant. 2017 May 18. doi: 10.1111/ctr.13011. [Epub ahead of print] PubMed

Liang X, Giacomini KM. Transporters Involved in Metformin Pharmacokinetics and Treatment Response. J Pharm Sci. 2017 May 8. pii: S0022-3549(17)30351-9. doi:10.1016/j.xphs.2017.04.078. [Epub ahead of print] PubMed

Samoylova ML, Nigrini MJ, Dodge JL, Roberts JP. Biases in the reporting of hcc tumor sizes on the liver transplant waiting list. Hepatology. 2017 May 18. doi: 10.1002/hep.29269. [Epub ahead of print] PubMed

Shneider BL, Moore J, Kerkar N, Magee JC, Ye W, Karpen SJ, Kamath BM, Molleston JP, Bezerra JA, Murray KF, Loomes KM, Whitington PF, Rosenthal P, Squires RH, Guthery SL, Arnon R, Schwarz KB, Turmelle YP, Sherker AH, Sokol RJ; Childhood Liver Disease Research Network. Initial assessment of the infant with neonatal cholestasis-Is this biliary atresia? PLoS One. 2017 May 11;12(5):e0176275. doi: 10.1371/journal.pone.0176275. eCollection 2017. PubMed

Tao J, Zhang R, Singh S, Poddar M, Xu E, Oertel M, Chen X, Ganesh S, Abrams M, Monga SP. Targeting β-catenin in hepatocellular cancers induced by coexpression of mutant β-catenin and K-Ras in mice. Hepatology. 2017 May;65(5):1581-1599. doi: 10.1002/hep.28975. Epub 2017 Feb 6. PubMed

Terrault NA, Berenguer M, Strasser SI, Gadano A, Lilly L, Samuel D, Kwo PY, Agarwal K, Curry MP, Fagiuoli S, Fung JYY, Gane E, Brown KA, Burra P, Charlton M, Pessoa MG, McCaughan GW. International Liver Transplantation Society Consensus Statement on Hepatitis C Management in Liver Transplant Recipients. Transplantation. 2017 May;101(5):956-967. doi: 10.1097/TP.0000000000001704. PubMed

Terrault NA, McCaughan GW, Curry MP, Gane E, Fagiuoli S, Fung JYY, Agarwal K, Lilly L, Strasser SI, Brown KA, Gadano A, Kwo PY, Burra P, Samuel D, Charlton M, Pessoa MG, Berenguer M. International Liver Transplantation Society Consensus Statement on Hepatitis C Management in Liver Transplant Candidates. Transplantation. 2017 May;101(5):945-955. doi: 10.1097/TP.0000000000001708. PubMed

Wirth S, Rosenthal P, Gonzalez-Peralta RP, Jonas MM, Balistreri WF, Chuan-Hao L, Hardikar W, Kersey K, Massetto B, Kanwar B, Brainard DM, Shao J, Svarovskaia E, Kirby B, Arnon R, Murray KF, Schwarz KB. Sofosbuvir and Ribavirin in Adolescents 12 to 17 Years Old With Hepatitis C Virus Genotype 2 or 3 Infection. Hepatology. 2017 May 22. doi: 10.1002/hep.29278. [Epub ahead of print] PubMed

Yang JY, Sarwal MM. Transplant genetics and genomics. Nat Rev Genet. 2017 May;18(5):309-326. doi: 10.1038/nrg.2017.12. Epub 2017 Mar 13. Review. PubMed


Balwani M, Naik H, Anderson KE, Bissell DM, Bloomer J, Bonkovsky HL, Phillips JD, Overbey JR, Wang B, Singal AK, Liu LU, Desnick RJ. Clinical, Biochemical, and Genetic Characterization of North American Patients With Erythropoietic Protoporphyria and X-linked Protoporphyria. JAMA Dermatol. 2017 Jun 14. doi: 10.1001/jamadermatol.2017.1557. [Epub ahead of print] PubMed

Balwani M, Wang B, Anderson KE, Bloomer JR, Bissell DM, Bonkovsky HL, Phillips JD, Desnick RJ; Porphyrias Consortium of the Rare Diseases Clinical Research Network. Acute Hepatic Porphyrias: Recommendations for Evaluation and Long Term Management. Hepatology. 2017 Jun 12. doi: 10.1002/hep.29313. [Epub ahead of print] PubMed

Braun HJ, Dodge JL, Roll GR, Freise CE, Ascher NL, Roberts JP. Impact of Graft Selection on Donor and Recipient Outcomes After Living Donor Liver Transplantation. Transplantation. 2016 Jun;100(6):1244-50. doi: 10.1097/TP.0000000000001101. PubMed

Dujic T, Zhou K, Yee SW, van Leeuwen N, de Keyser CE, Javorský M, Goswami S, Zaharenko L, Hougaard Christensen MM, Out M, Tavendale R, Kubo M, Hedderson MM, van der Heijden AA, Klimčáková L, Pirags V, Kooy A, Brøsen K, Klovins J, Semiz S, Tkáč I, Stricker BH, Palmer C, 't Hart LM, Giacomini KM, Pearson ER. Variants in Pharmacokinetic Transporters and Glycemic Response to Metformin: A Metgen Meta-Analysis. Clin Pharmacol Ther. 2017 Jun;101(6):763-772. doi: 10.1002/cpt.567. Epub 2017 Feb 3. PubMed

Giard JM, Terrault NA. Women with Cirrhosis: Prevalence, Natural History, and Management. Gastroenterol Clin North Am. 2016 Jun;45(2):345-58. doi: 10.1016/j.gtc.2016.02.010. Review. PubMed

Wang CW, Lai JC. Reporting functional status in UNOS: The weakness of the Karnofsky Performance Status Scale. Clin Transplant. 2017 Jun 5. doi:10.1111/ctr.13004. [Epub ahead of print] PubMed PMID:. PubMed

Webb BA, Dosey AM, Wittmann T, Kollman JM, Barber DL. The glycolytic enzyme phosphofructokinase-1 assembles into filaments. J Cell Biol. 2017 Jun 23. pii: jcb.201701084. doi: 10.1083/jcb.201701084. [Epub ahead of print] PubMed

White UA, Fitch MD, Beyl RA, Hellerstein MK, Ravussin E. Differences in In Vivo Cellular Kinetics in Abdominal and Femoral Subcutaneous Adipose Tissue in Women. Diabetes. 2016 Jun;65(6):1642-7. doi: 10.2337/db15-1617. Epub 2016 Mar 18. PubMed

Yulyaningsih E, Rudenko IA, Valdearcos M, Dahlén E, Vagena E, Chan A, Alvarez-Buylla A, Vaisse C, Koliwad SK, Xu AW. Acute Lesioning and Rapid Repair of Hypothalamic Neurons outside the Blood-Brain Barrier. Cell Rep. 2017 Jun 13;19(11):2257-2271. doi: 10.1016/j.celrep.2017.05.060. PubMed