Time:
9:00AM-10:00AM
Location:
S-214, Parnassus
Hao Zhu, MD
Associate Professor, UT Southwestern Medical Center
Interrogating the Genomics of Liver Regeneration and Cancer with Mouse Models
We seek to determine if the ability to regenerate and repair lost tissues increases or decreases the risk of cancer. Although it is assumed that increased regenerative capacity confers greater cancer risk, we hypothesize that the potent regenerative abilities of the skin, intestine, and liver could serve to preserve tissue integrity, reduce inflammation, and resist transformation in the context of recurrent injury. We bring this question to bear on the problem of liver disease and hepatocellular carcinoma, which most frequently arises in chronically damaged livers.
Host: Bruce Wang, MD
