Sang-Mo Kang, MD
Research Interests
My lab studies the regulation of immune tolerance, with the ultimate objective of finding ways to induce tolerance and thus facilitate long-term engraftment of transplanted organs. We use cell culture as well as animal models to study mechanisms of allograft rejection. Of particular interest is the “tolerogenic” nature of liver transplants, which are spontaneously tolerated across full MHC mismatches in mice. Lessons learned from the immunobiology of the liver can hopefully be extrapolated to other organs.
Selected Publications
- Garrod KG, Chang CK, Liu FC, Brennan TV, Foster RD, Kang SM. Targeted lymphoid homing of dendritic cells is required for prolongation of allograft survival. J Immunol 2006; 177:863-868.
- Kim J, Chang GC, Hayden T, Liu FC, Benjamin J, Hameman JA, Lanier LL, and Kang SM. The Activating Immunoreceptor NKG2D and Its Ligands are Involved in Allograft Transplant Rejection. J Immunol 2007;179:6416-6420.
- Brennan TV, Hoang V, Garrod KR, Liu F-C, Hayden T, Kim J, and Kang SM. A New TCR Transgenic Model of the CD4+ Direct Pathway: Level of Priming Determines Acute versus Chronic Rejection. Transplantation 2008;85:247-255.
- Associate Professor
- Surgery/Transplant Surgery
Research Theme
- Liver Injury and Repair
Contact Information
- kangs@
surgery.ucsf.edu - Phone: (415) 353-8783
- Fax: (415) 514-2982
- 505 Parnassus Ave.
- Box 0116, M-884
- San Francisco, CA 94143-0116
Other UCSF Affiliations
- Hellen Diller Family Comprehensive Cancer Center