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Lab Manual for Moffitt-Long and Mount Zion

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Peter Bacchetti, PhD

Research Interests

I am currently working on new methods for modeling biopsy-measured fibrosis progression. I also contribute to a variety of liver-related research projects in my role as collaborator and director of the CTSI’s Biostatistical Unit. Current work for the Liver Center addresses how alcohol consumption influences progression of HCV, the impact of hepatitis viruses in HIV-infected patients, and the influence of HCV on glucose metabolism. My activities on these studies include advising on data collection instruments and procedures, meeting with investigators to clarify goals, developing and implementing analysis plans, interpreting results, and contributing to original publications. Many of these collaborations require innovative use of modem statistical methods, such as mixed effects models with multiple random effects and use of bootstrapping to obtain valid confidence intervals and p-values when assumptions for standard methods are not met.

Selected Publications

  • Bacchetti P, Tien PC, Seaberg EC, O’Brien TR, Augenbraun MH, Kral AH, Busch MP, Edlin BR. Estimating past hepatitis C infection risk from reported risk factor histories: implications for imputing age of infection and modeling fibrosis progression. BMC Infectious Diseases 2007; 7:145.
  • Ishida JH, Peters MG, Jin C, Louie K, Tan V, Bacchetti P, Terrault NA. Influence of cannabis use on severity of hepatitis C disease. Clinical Gastroenterol Hepatol 2008;6:69-75.
  • Bacchetti P, McCulloch CE, Segal MR. Simple, defensible sample sizes based on cost efficiency. Biometrics 2008, in press.
Peter Bacchetti, Ph.D.
  • Professor
  • Epidemiology and Biostatistics

Research Theme

  • Liver Injury and Repair

Contact Information

  • 185 Berry Street 5700
  • Box 0560
  • San Francisco, CA. 94143 — 0560

Other UCSF Affiliations

  • Hellen Diller Family Comprehensive Cancer Center
  • Clinical and Translational Sciences Institute

Website

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