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Michael P. Busch, MD, PhD

Research Interests

My major research interests include the epidemiology, natural history, pathogenesis, and laboratory evaluation of transfusion-associated viral infections, the immunological consequences of allogeneic transfusion, and mechanisms of viral latency and reactivation following transfusion or other immunological stimuli. My laboratory is the Central Laboratory for the recently launched US and International REDS-II program, the major NIH-funded initiative supporting transfusion medicine research focused on blood safety and availability in the US and abroad. My laboratory also studies the natural history and pathogenesis of HCV infection in the blood donor and recipient settings, with the objective of defining rates and determinants of viral clearance and as well as rates and determinants for the developing liver disease.

Selected Publications

  • Page K, Osburn W, Evans J, Hahn JA, Lum P, Asher A, Delwart E, Tobler L, Cox AL, Busch MP. Frequent longitudinal sampling of HCV infection in IDU reveals
    intermittently detectable viremia and reinfection. Clin Infect Dis. 2012 Oct 22. [Epub ahead of print]
  • Bloch EM, Jackman RP, Lee TH, Busch MP. Transfusion-Associated Microchimerism: The Hybrid Within. Transfus Med Rev. 2012 Oct 23.
  • de Almeida-Neto C, Sabino EC, Liu J, Blatyta PF, Mendrone-Junior A, Salles NA, Leão SC, Wright DJ, Basques FV, Ferreira JE, Busch MP, Murphy EL; NHLBI Retrovirus Epidemiology Donor Study-II (REDS-II), International Component. Prevalence of serologic markers for hepatitis B and C viruses in Brazilian blood  donors and incidence and residual risk of transfusion transmission of hepatitis C virus. Transfusion. 2012 Aug 6.

Michael P. Busch, M.D., Ph.D.
  • Professor
  • Laboratory Medicine
  • Director, Blood Systems Research Institute

Research Theme

  • Liver Injury and Repair

Contact Information

  • Blood Systems Research Institute
  • 270 Masonic Avenue
  • San Francisco, CA. 94118


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