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Charles Harris, MD, PhD

Research Interests

My research focuses on mechanisms of lipid storage. In particular I am interested in the metabolic effects of glucocorticoids. Specifically, with respect to the liver I am interested in the mechanistic basis for glucocorticoid mediated hepatic insulin resistance. A second area of interest is the roles of the DGAT enzymes, which catalyze the final step in triglyceride synthesis, in health and disease. For example, in a recent collaboration with Melanie Ott’s laboratory we are studying the role of DGAT1 in hepatitis C infection.

Selected Publications

  • CA Harris, K Veenstra, S Marmor, B Hubbard, B Halloran, RV Farese.Transgenic Cushingoid Mice Model the Obesogenic, Diabetogenic, and Catabolic Effects of Glucocorticoid Excess (in preparation).
  • Herker E, Harris C, Farese RV Jr, Ott M. Diacylglycerol Acyltransferase 1 is a Crucial Host Factor for Hepatitis C Virus Replication. (submitted).
  • Harris C, Yen CL, Stone SJ, Koliwad S, Farese RV Jr. (2008) DGAT enzymes and triacylglycerol biosynthesis. J Lipid Res. 49(11):2283-301.
Charles Harris
  • Assistant Adjunct Professor
  • Medicine/Endocrinology

Research Theme

  • Hepatic Physiology and Metabolism

Contact Information

  • Mission Bay Campus                                          Box 1230
  • 1650 Owen Street, Fourth Floor
  • San Francisco, CA. 94158

Other UCSF Affiliations

The University of California, San Francisco. ©2008 The Regents of the University of California

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