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Aliya Qayyum, MD

Research Interests

My research focuses on the noninvasive distinction of nonalcoholic steatohepatitis (NASH) from simple hepatic steatosis. We are investigating the possibility that non-invasive MRI markers of steatosis, inflammation and fibrosis will provide equivalent and/or additional diagnostic information to liver biopsy in patients with nonalcoholic fatty liver disease. Specifically, we are evaluating apparent diffusion coefficient (ADC) values derived from diffusion MR imaging as well as MR spectroscopic (MRS) markers (lipids, water, and choline containing compounds) as possible diagnostic markers of NASH. ADC values and MRS markers may also correlate with the stage of fibrosis in NASH.

Selected Publications

  • Westphalen AC, Qayyum A, Yeh BM, Merriman RB, Lee JA, Lamba A, Lu Y, Coakley FV. Liver fat: effect of hepatic iron deposition on evaluation with opposed-phase MR imaging. Radiology 2007;242:450-5.
  • Keedy A, Westphalen AC, Qayyum A, Aslam R, Rybkin AV, Chen MH, Coakley FV. Diagnosis of cirrhosis by spiral computed tomography: a case-control study with feature analysis and assessment of interobserver agreement. J Comput Assist Tomogr 2008;32:198-203.
  • Taouli B, Chouli M, Martin AJ, Qayyum A, Coakley FV, Vilgrain V. Chronic hepatitis: role of diffusion-weighted imaging and diffusion tensor imaging for the diagnosis of liver fibrosis and inflammation. J Magn Reson Imaging 2008;28:89-95.
Zoltan G. Laszik, M.D., Ph.D.
  • Associate Professor
  • Radiology/Abdominal Imaging

Research Theme

  • Hepatic Physiology and Metabolism

Contact Information

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