Latest News
Center Updates
Center announces the recipients of 2009-2010 Pilot Feasibility Grants
The Center is pleased to announce the following Pilot Feasibility grant awardees:
- Katerina Akassoglou, Gladstone Neurobiology "Study of the Evolutionarily Conserved Functions of the Neurotrophin Receptor p75NTR"
- Carlos Corvera, Department of Surgery "The Role of Membrane Bound Bile Acid Receptor (GpBAR1) in Pruritus"
- Eva Herker and Charles Harris, Gladstone Cardiology/Virology "Role of DGAT1 in Hepatitis C Virus core protein-induced steatosis and lipoprotein secretion"
- Mike McCune and collaborators, Department of Medicine (Experimental Medicine) "The maternal-fetal interface during maternal hepatitis C virus infection"
- Ethan Weiss, Department of Medicine (Cardiology) "Characterizing Fatty Liver in Hepatocyte-Specific JAK2 Deficient Mice"
Center welcomes its newest External Advisory Board member
The Center is honored to announce that Dr. D. Brent Polk will be joining the External Advisory Board. Dr. Polk is Chief of the Division of Pediatric Gastroenterology at Vanderbilt University, and Program Director for the Vanderbilt Digestive Disease Research Center. Dr. Polk's research focuses on intestinal cell signaling in inflammation and tumorigenesis. His knowledge of GI cell biology and DDRCC administration will be great assets to the Center.
Center awards its second Tool and Technology Grants
The Center is pleased to announce Drs. Jody Baron, Scott Biggins, and Melanie Ott as the recipients of the second round of Tool and Technology grant funding. For more information on the Tool and Technology program including application instructions (next applications due Wednesday, July 1, 2009), please view the Tool and Technology Grant Program.
New Immunology & Virology Core Personnel
The Center welcomes Amanda Goodsell as the research specialist for the Immunology & Virology Core. Amanda has worked in academia and biotechnology for 12 years, most recently with Chiron/Novartis Vaccines and Diagnostics. In the Immunology & Virology Core, Amanda will maintain the LSRII flow cytometer and assist Center members with experiments and study design. She will also complete development of a quantitative RT-PCR assay for HBV DNA in biological samples, which will soon be available for a modest recharge.
New Reduced prices for the Pathology & Imaging Core
The new prices will be effective starting June 1, 2009 for all members.
Please go to the Pathology & Imaging Core page for the new price listings!
Upcoming Liver Center Seminars/Events
Thank you to all for coming to and making the 2009 External Advisory Board Symposium a success! We look forward to seeing you at the next event.
Liver Center Seminar Series
June 17, 2009 @ 9AM, Room S-214, Laura Bull, PhD "Genetic Mapping of Modifier Genes in the Atp8b1 (Fic1) Mutant Mouse"
Work in Progress Seminar Series
June 19, 2009 @ 1PM, Room N-729 (NEW time and room) Amnon Schlegel, MD, PhD "A Molecular Genetic Approach to Studying Hepatic Lipid Metabolism"
Recent Publications
Tanimizu N, Miyajima A, Mostov KE. Liver progenitor cells fold up a cell monolayer into a double-layered structure during tubular morphogenesis. Mol Biol Cell. 2009 May;20(9):2486-94. Epub 2009 Mar 18. PubMed PMID: 19297530; PubMed Central PMCID: PMC2675627.
Kakar S, Chen X, Ho C, Burgart LJ, Sahai V, Dachrut S, Yabes A, Jain D, Ferrell LD. Chromosomal changes in fibrolamellar hepatocellular carcinoma detected by array comparative genomic hybridization. Mod Pathol. 2009;22(1)134-41.
Wang Y, Liao M, Hoe N, Acharya P, Deng C, Krutchinsky AN, Correia MA. A role for protein phosphorylation in cytochrome P450 3A4 ubiquitin-dependent proteasomal degradation. J Biol Chem. 2009;184(9):5671-5684.
Aanstad P, Santos N, Corbit KC, Scherz PJ, Trinh LA, Salvenmoser W, Huisken J, Reiter JF, Stainier DY. The Extracellular Domain of Smoothened Regulates Ciliary Localization and Is Required for High-Level Hh Signaling. Curr Biol. 2009 May 20.[Epub ahead of print] PubMed PMID: 19464178.